abstract：:Morphine remains widely used in clinical settings due to its potent analgesic properties. However, one of the gravest risks of all opioids is their ability to induce respiratory depression and subsequent brain hypoxia that can lead to coma and death. Due to these life-threatening effects, our goal was to examine the e...

journal_title：Journal of neurophysiology

authors： Solis E Jr,Afzal A,Kiyatkin EA

更新日期：2018-11-01 00:00:00

abstract：:A voluntary contraction of muscles with one arm increases the excitability of corticospinal projections to the contralateral resting arm, a phenomenon known as crossed facilitation. Although many motor tasks engage simultaneous activation of the arm and trunk, interactions between corticospinal projections targeting t...

journal_title：Journal of neurophysiology

authors： Chiou SY,Strutton PH,Perez MA

更新日期：2018-11-01 00:00:00

abstract：:In free viewing, the eyes return to previously visited locations rather frequently, even though the attentional and memory-related processes controlling eye-movement show a strong antirefixation bias. To overcome this bias, a special refixation triggering mechanism may have to be recruited. We probed the neural eviden...

journal_title：Journal of neurophysiology

authors： Nikolaev AR,Meghanathan RN,van Leeuwen C

更新日期：2018-11-01 00:00:00

abstract：:When the brain has determined the position of a moving object, because of anatomical and processing delays the object will have already moved to a new location. Given the statistical regularities present in natural motion, the brain may have acquired compensatory mechanisms to minimize the mismatch between the perceiv...

journal_title：Journal of neurophysiology

authors： Subramaniyan M,Ecker AS,Patel SS,Cotton RJ,Bethge M,Pitkow X,Berens P,Tolias AS

更新日期：2018-11-01 00:00:00

abstract：:Older adults are at a high risk of falls, and most falls occur during locomotor activities like walking. This study aimed to improve our understanding of changes in neuromuscular control associated with increased risk of falls in older adults in the presence of dynamic balance challenges during walking. Motor module (...

journal_title：Journal of neurophysiology

authors： Allen JL,Franz JR

更新日期：2018-11-01 00:00:00

abstract：:Successful motor performance relies on our ability to adapt to changes in the environment by learning novel mappings between motor commands and sensory outcomes. Such adaptation is thought to involve two distinct mechanisms: an implicit, error-based component linked to slow learning and an explicit, strategic componen...

journal_title：Journal of neurophysiology

authors： de Brouwer AJ,Albaghdadi M,Flanagan JR,Gallivan JP

更新日期：2018-10-01 00:00:00

abstract：:The current eye-tracking study examined the influence of reward on oculomotor performance, and the extent to which learned stimulus-reward associations interacted with voluntary oculomotor control with a modified paradigm based on the classical antisaccade task. Participants were shown two equally salient stimuli simu...

journal_title：Journal of neurophysiology

authors： Preciado D,Theeuwes J

更新日期：2018-10-01 00:00:00

abstract：:The purpose of our study was to examine the associations between the performance of older adults on four tests of mobility and the physical capabilities of the lower leg muscles. The assessments included measures of muscle strength, muscle activation, and perceived fatigability. Muscle activation was quantified as the...

journal_title：Journal of neurophysiology

authors： Mani D,Almuklass AM,Hamilton LD,Vieira TM,Botter A,Enoka RM

更新日期：2018-10-01 00:00:00

abstract：:The nucleus accumbens core (AcbC) is a striatal brain region essential for integrating motivated behavior and reward processing with premotor function. In humans and rodents, research has identified sex differences and sex steroid hormone sensitivity in AcbC-mediated behaviors, in disorders, and in rats in the electro...

journal_title：Journal of neurophysiology

authors： Cao J,Dorris DM,Meitzen J

更新日期：2018-10-01 00:00:00

abstract：:The timing of brief stationary sounds has been shown to alter the perceived speed of visual apparent motion (AM), presumably by altering the perceived timing of the individual frames of the AM stimuli and/or the duration of the interstimulus intervals (ISIs) between those frames. To investigate the neural correlates o...

journal_title：Journal of neurophysiology

authors： Kafaligonul H,Albright TD,Stoner GR

更新日期：2018-09-01 00:00:00

abstract：:Individuals with cerebral palsy (CP) experience impairments in the control of head and neck movements, suggesting dysfunction in brain stem circuitry. To examine if brain stem circuitry is altered in CP, we compared reflexes evoked in the sternocleidomastoid (SCM) muscle by trigeminal nerve stimulation in adults with ...

journal_title：Journal of neurophysiology

authors： Smith AT,Gorassini MA

更新日期：2018-09-01 00:00:00

abstract：:The respiratory network of the preBötzinger complex (preBötC), which controls inspiratory behavior, can in normal conditions simultaneously produce two types of inspiration-related rhythmic activities: the eupneic rhythm composed of monophasic, low-amplitude, and relatively high-frequency bursts, interspersed with sig...

journal_title：Journal of neurophysiology

authors： Thoby-Brisson M

更新日期：2018-09-01 00:00:00

abstract：:Parkinson's disease is associated with altered neural activity in the motor cortex. Chronic high-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in suppressing parkinsonian motor symptoms and modulates cortical activity. However, the anatomical pathways responsible for STN DBS-medi...

journal_title：Journal of neurophysiology

authors： Kumaravelu K,Oza CS,Behrend CE,Grill WM

更新日期：2018-08-01 00:00:00

abstract：:Successful negotiation of obstacles during walking relies on the integration of visual information about the environment with ongoing locomotor commands. When information about the body and the environment is removed through occlusion of the lower visual field, individuals increase downward head pitch angle, reduce fo...

journal_title：Journal of neurophysiology

authors： Kim A,Kretch KS,Zhou Z,Finley JM

更新日期：2018-08-01 00:00:00

abstract：:Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of t...

journal_title：Journal of neurophysiology

authors： Jimenez LO,Tring E,Trachtenberg JT,Ringach DL

更新日期：2018-07-01 00:00:00

abstract：:We developed a sway-referenced system for sitting to highlight the role of vestibular and visual contributions to trunk control. Motor control was investigated by measuring trunk kinematics in the frontal plane while manipulating visual availability and introducing a concurrent cognitive task. We examined motor learni...

journal_title：Journal of neurophysiology

authors： Goodworth AD,Tetreault K,Lanman J,Klidonas T,Kim S,Saavedra S

更新日期：2018-07-01 00:00:00

abstract：:Compression apparel is popular in both medical and sport performance settings. Perceived benefits are suggested to include changes in sensory feedback transmission caused by activation of mechanoreceptors. However, little is known about effects of compression apparel on sensorimotor control. Our purpose was to mechani...

journal_title：Journal of neurophysiology

authors： Barss TS,Pearcey GEP,Munro B,Bishop JL,Zehr EP

更新日期：2018-07-01 00:00:00

abstract：:The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the exclusive relay of retinal information en route to the visual cortex. Although much of our understanding about dLGN comes from studies done in higher mammals, such as the cat and primate, the mouse as a model organism has moved to the forefront as a t...

journal_title：Journal of neurophysiology

authors： Guido W

更新日期：2018-07-01 00:00:00

abstract：:Evidence first described in reduced animal models over 100 years ago led to deductions about the control of locomotion through spinal locomotor central pattern-generating (CPG) networks. These discoveries in nature were contemporaneous with another form of deductive reasoning found in popular culture, that of Arthur C...

journal_title：Journal of neurophysiology

authors： Klarner T,Zehr EP

更新日期：2018-07-01 00:00:00

abstract：:People perceive better in cardinal directions compared with oblique ones. This directional effect, called oblique effect, has been documented in perception studies for a long time. However, typical motor studies do not differentiate learning in different directions. In this study we identify a significant directional ...

journal_title：Journal of neurophysiology

authors： Jiang W,Yuan X,Yin C,Wei K

更新日期：2018-07-01 00:00:00

abstract：:Poststroke pain syndrome (PSPS) is an often intractable disorder characterized by hemiparesis associated with unrelenting chronic pain. Although traditional analgesics have largely failed, integrative approaches targeting affective-cognitive spheres have started to show promise. Recently, we demonstrated that deep bra...

journal_title：Journal of neurophysiology

authors： Gopalakrishnan R,Burgess RC,Malone DA,Lempka SF,Gale JT,Floden DP,Baker KB,Machado AG

更新日期：2018-06-01 00:00:00

abstract：:Individuals who have experienced a stroke often demonstrate inappropriate muscle activity phasing in the paretic leg during locomotion. Past research has demonstrated that inappropriate paretic phasing varies between behavioral contexts and is reduced during unilateral pedaling with the nonparetic leg inactive. We inv...

journal_title：Journal of neurophysiology

authors： Mullens CH,Brown DA

更新日期：2018-06-01 00:00:00

abstract：:Following the groundbreaking discovery of grid cells, the medial entorhinal cortex (MEC) has become the focus of intense anatomical, physiological, and computational investigations. Whether and how grid activity maps onto cell types and cortical architecture is still an open question. Fundamental similarities in micro...

journal_title：Journal of neurophysiology

authors： Naumann RK,Preston-Ferrer P,Brecht M,Burgalossi A

更新日期：2018-06-01 00:00:00

abstract：:When people match an unseen hand to a visual or proprioceptive target, they make both variable and systematic (bias) errors. Variance is a well-established factor in behavior, but the origin and implications of bias, and its connection to variance, are poorly understood. Eighty healthy adults matched their unseen righ...

journal_title：Journal of neurophysiology

authors： Liu Y,Sexton BM,Block HJ

更新日期：2018-05-01 00:00:00

abstract：:The spinal cord has been well established as the site of generation of the locomotor rhythm in vertebrates, but studies have suggested that the caudal hindbrain in larval fish and amphibians can also generate locomotor rhythms. Here, we investigated whether the caudal hindbrain of the adult lamprey ( Petromyzon marinu...

journal_title：Journal of neurophysiology

authors： Buchanan JT

更新日期：2018-05-01 00:00:00

abstract：:Multisite optical recording has revealed that the neural excitation wave induced by a sensory stimulation begins at a focus and propagates in the cortex. This wave is considered to be important for computation in the sensory cortex, particularly the integration of sensory information; however, the nature of this wave ...

journal_title：Journal of neurophysiology

authors： Hama N,Kawai M,Ito SI,Hirota A

更新日期：2018-05-01 00:00:00

abstract：:Our continuous perception of the world could be the result of discrete sampling, where individual snapshots are seamlessly fused into a coherent stream. It has been argued that endogenous oscillatory brain activity could provide the functional substrate of cortical rhythmic sampling. A new study demonstrates that cort...

journal_title：Journal of neurophysiology

authors： Helfrich RF

更新日期：2018-04-01 00:00:00

abstract：:The human visual system is remarkably sensitive to environmental regularities, which can facilitate behavioral performance when sensory events conform to past experience. The point at which prior knowledge is integrated during visual perception is unclear, particularly for incidentally learned associations. One possib...

journal_title：Journal of neurophysiology

authors： Hall MG,Mattingley JB,Dux PE

更新日期：2018-04-01 00:00:00

abstract：:Response adaptation is the change of the firing rate of neurons induced by a preceding stimulus. It can be found in many sensory systems and throughout the auditory pathway. We investigated response adaptation in the external nucleus of the inferior colliculus (ICX) of barn owls ( Tyto furcata), a nocturnal bird of pr...

journal_title：Journal of neurophysiology

authors： Ferger R,Pawlowsky K,Singheiser M,Wagner H

更新日期：2018-03-01 00:00:00

abstract：:The caudal mesopallium (CM) is a cortical-level area in the songbird auditory pathway where selective, invariant responses to familiar songs emerge. To characterize the cell types that perform this computation, we made whole cell recordings from brain slices in juvenile zebra finches ( Taeniopygia guttata) of both sex...

journal_title：Journal of neurophysiology

authors： Chen AN,Meliza CD

更新日期：2018-03-01 00:00:00

abstract：:The excitotoxic theory of Parkinson's disease (PD) hypothesizes that a pathophysiological degeneration of dopaminergic neurons stems from neural hyperactivity at early stages of disease, leading to mitochondrial stress and cell death. Recent research has harnessed the visual system of Drosophila PD models to probe thi...

journal_title：Journal of neurophysiology

authors： Himmelberg MM,West RJH,Elliott CJH,Wade AR

更新日期：2018-03-01 00:00:00

abstract：:The locus coeruleus (LC) noradrenergic (NE) neuromodulatory system is critically involved in regulation of neural excitability via its diffuse ascending projections. Tonic NE release in the forebrain is essential for maintenance of vigilant states and increases the signal-to-noise ratio of cortical sensory responses. ...

journal_title：Journal of neurophysiology

authors： Neves RM,van Keulen S,Yang M,Logothetis NK,Eschenko O

更新日期：2018-03-01 00:00:00

abstract：:The blood oxygen level-dependent (BOLD) functional magnetic resonance imaging signal arises as a consequence of changes in blood flow and oxygen usage that in turn are modulated by changes in neural activity. Much attention has been given to both theoretical and experimental aspects of the energetics but not to the ne...

journal_title：Journal of neurophysiology

authors： Bennett MR,Farnell L,Gibson WG

更新日期：2018-03-01 00:00:00

abstract：:CA1 place cells become more anticipatory with experience, an effect thought to be caused by NMDA receptor-dependent plasticity in the CA3-CA1 network. Theta (~5-12 Hz), slow gamma (~25-50 Hz), and fast gamma (~50-100 Hz) rhythms are thought to route spatial information in the hippocampal formation and to coordinate pl...

journal_title：Journal of neurophysiology

authors： Gereke BJ,Mably AJ,Colgin LL

更新日期：2018-02-01 00:00:00

abstract：:The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...

journal_title：Journal of neurophysiology

authors： Stewart CE,Kanicki AC,Altschuler RA,King WM

更新日期：2018-02-01 00:00:00

abstract：:We presented optic flow and real movement heading stimuli while recording MSTd neuronal activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow heading perturbations, vestibular detection of real movement heading perturbations, and auditory detection of brief tones. Push-button RTs we...

journal_title：Journal of neurophysiology

authors： Page WK,Duffy CJ

更新日期：2018-01-01 00:00:00

abstract：:As a vital skill in an evolving world, interception of moving objects relies on accurate prediction of target motion. In natural circumstances, active gaze shifts often accompany hand movements when exploring targets of interest, but how eye and hand movements are coordinated during manual interception and their depen...

journal_title：Journal of neurophysiology

authors： Li Y,Wang Y,Cui H

更新日期：2018-01-01 00:00:00

abstract：:It has recently become clear that microglia, the immune cells of the central nervous system, are far more active in the healthy brain than previously thought. Microglia facilitate many stages of brain development by shaping neuronal connectivity via synaptic elimination. Dysfunction of these same processes likely unde...

journal_title：Journal of neurophysiology

authors： Whitelaw BS

更新日期：2018-01-01 00:00:00

abstract：:In the mammalian vestibular periphery, electrical activation of the efferent vestibular system (EVS) has two effects on afferent activity: 1) it increases background afferent discharge and 2) decreases afferent sensitivity to rotational stimuli. Although the cellular mechanisms underlying these two contrasting afferen...

journal_title：Journal of neurophysiology

authors： Poppi LA,Tabatabaee H,Drury HR,Jobling P,Callister RJ,Migliaccio AA,Jordan PM,Holt JC,Rabbitt RD,Lim R,Brichta AM

更新日期：2018-01-01 00:00:00

abstract：:Over the past decade neuroscientific research has attempted to probe the neurobiological underpinnings of human prosocial decision making. Such research has almost ubiquitously employed tasks such as the dictator game or similar variations (i.e., ultimatum game). Considering the explicit numerical nature of such tasks...

journal_title：Journal of neurophysiology

authors： Arshad Q,Nigmatullina Y,Siddiqui S,Franka M,Mediratta S,Ramachandaran S,Lobo R,Malhotra PA,Roberts RE,Bronstein AM

更新日期：2017-12-01 00:00:00